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Invited Commentary
January 2019

Should Aspirin Be Routinely Used for Venous Thromboembolism Prophylaxis After Total Knee Arthroplasty?Even the Authors of This Commentary Cannot Agree

Author Affiliations
  • 1Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 2Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 3The Armstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine, Baltimore, Maryland
JAMA Surg. 2019;154(1):72-73. doi:10.1001/jamasurg.2018.3859

Venous thromboembolism (VTE) is a recognized risk after total knee arthroplasty (TKA).1 While nearly all orthopedic surgeons agree that pharmacologic prophylaxis is the standard of care, major disagreements remain about the optimal, or even acceptable, medication regimens. Even evidence-based guidelines from different national societies,2,3 using the same published literature, often make different recommendations.4

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