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Comment & Response
November 21, 2018

Utility of Bladder-Sparing Therapy vs Radical Cystectomy for Muscle-Invasive Bladder Cancer

Author Affiliations
  • 1Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston
  • 2The University of Manchester and The Christie NHS Foundation Trust, Manchester, United Kingdom
  • 3CRUK/MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom
JAMA Surg. 2019;154(2):184-185. doi:10.1001/jamasurg.2018.4370

To the Editor Williams et al1 used the Surveillance, Epidemiology, and End Results–Medicare linked database to compare radical cystectomy (RC) with trimodal therapy (TMT) for treatment of muscle-invasive bladder cancer (MIBC) in older adults. Using propensity score matching, they concluded that TMT was associated with significantly decreased survival as well as increased costs.

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