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Comment & Response
November 21, 2018

Utility of Bladder-Sparing Therapy vs Radical Cystectomy for Muscle-Invasive Bladder Cancer

Author Affiliations
  • 1Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore
JAMA Surg. Published online November 21, 2018. doi:10.1001/jamasurg.2018.4371

To the Editor We read with great interest the article by Williams et al1 evaluating the Surveillance, Epidemiology and End Results (SEER)–Medicare linked database to compare outcomes and cost of radical cystectomy (RC) with trimodal bladder preservation therapy (BPT) for older patients with muscle-invasive bladder cancer. Using propensity score matching, the authors demonstrate improved survival and decreased costs for RC. However, we would like to caution readers on several points.

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