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Comment & Response
November 28, 2018

Quantifying the Added Value of Low-Molecular-Weight Heparin to Intermittent Pneumatic Compression for Preventing Venous Thromboembolic Events Under the Risk-Benefit Perspective—Reply

Author Affiliations
  • 1Division of Gastrointestinal Surgery, Department of Surgery, Seoul St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
JAMA Surg. Published online November 28, 2018. doi:10.1001/jamasurg.2018.4306

In Reply We thank McCaw et al for their interest in our article.1 They commented that it would be useful to combine efficacy and safety at the individual level through a composite end point. They also suggested that intermediary categories can be constructed to quantify degrees of partial response, which can create a descriptive categorical composite end point. From this approach, the result can be changed favoring intermittent pneumatic compression (IPC) group with an event difference rate of 4.9%. We are very interested in this idea.

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