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Comment & Response
February 13, 2019

Interest of Eosinophil Count in Bacterial Infections to Predict Antimicrobial Therapy Efficacy

Author Affiliations
  • 1Maladies Infectieuses, Hôpital Universitaire Raymond-Poincaré, Assistance Publique–Hôpitaux de Paris, Garches, France
JAMA Surg. 2019;154(5):464. doi:10.1001/jamasurg.2018.5578

To the Editor We read with great interest the article published by Kulaylat et al1 concerning the use of peripheral eosinopenia to predict the outcomes of 2065 patients with Clostridium difficile infections (CDIs). In multivariate analysis, the authors found that undetectable eosinophil count was associated with increased in-hospital mortality and therefore was a marker of sepsis severity and admission in intensive care units. As CDI is one of the most common causes of nosocomial infection in the Unites States2 and has a high mortality rate, some points could be discussed.

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