To the Editor We read with great interest the article published by Kulaylat et al1 concerning the use of peripheral eosinopenia to predict the outcomes of 2065 patients with Clostridium difficile infections (CDIs). In multivariate analysis, the authors found that undetectable eosinophil count was associated with increased in-hospital mortality and therefore was a marker of sepsis severity and admission in intensive care units. As CDI is one of the most common causes of nosocomial infection in the Unites States2 and has a high mortality rate, some points could be discussed.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Davido B, de Truchis P, Dinh A. Interest of Eosinophil Count in Bacterial Infections to Predict Antimicrobial Therapy Efficacy. JAMA Surg. Published online February 13, 2019. doi:10.1001/jamasurg.2018.5578
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: