To the Editor We read with great interest the original investigation by Birenbaum et al1 entitled “Effect of Cricoid Pressure Compared With a Sham Procedure in the Rapid Sequence Induction of Anesthesia: The IRIS Randomized Clinical Trial.” We congratulate the IRIS investigators for completing an important trial and were impressed by the authors’ ability to design and conduct such a randomized clinical trial on the efficacy of cricoid pressure (CP). Such a study has long been categorized as unfeasible by experts in the fields.2,3 Ethical considerations3 and challenges in training for application of recommended cricoid force targets4 were among the feasibility issues reported. The study was well conducted and appears to have excellent internal validity.
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Noll E, Diemunsch P, Bennett-Guerrero E. Utility of Cricoid Pressure. JAMA Surg. Published online February 27, 2019154(6):562–563. doi:10.1001/jamasurg.2018.5848
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