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Comment & Response
March 6, 2019

Which Aspirin to Choose?—Reply

Author Affiliations
  • 1Department of Orthopaedic Surgery, University of Michigan, Ann Arbor
JAMA Surg. 2019;154(6):565-566. doi:10.1001/jamasurg.2019.0121

In Reply On behalf of my colleagues, I thank Gnecchi-Ruscone and Restifo Pecorella for their letter and questions about our research. We agree that the dosage of aspirin is important, but as explained in the Limitations section of our article,1 we unfortunately do not have that information in the registry. As part of our education program at our quality meetings, we advocated for the use of low-dose aspirin, as recommended in the Antithrombotic Therapy and Prevention of Thrombosis, 9th ed,2 but we do not know what dose was actually given. In addition, as is the case with all discharge medications, compliance may be an issue, so our study is based on the surgeon’s recommended or prescribed anticoagulation postoperatively.3

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