To the Editor With great interest, we read the article by Xu et al.1 The authors investigated the risk factors, patterns, and predictors of long-term outcomes in 734 patients with and without late hepatocellular carcinoma (HCC) recurrence after curative resection.
In the statistical analyses, we would like to suggest reanalyzing the data without the 112 patients with late recurrence receiving irregular surveillance to strengthen the results of this study. Those patients were diagnosed as having recurrence because of symptoms. Therefore, they might have had early recurrence if they had received regular surveillance. This might influence the results of the study.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Okubo K, Moro A, Sasaki K. Care After Liver Resection for Hepatocellular Carcinoma. JAMA Surg. Published online March 20, 2019154(6):568–569. doi:10.1001/jamasurg.2019.0149
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: