Surgical site infections (SSIs) are among the most common and costly health care–associated infections.1 While the goal of perioperative antimicrobial prophylaxis is to prevent SSIs, antibiotic misuse is widespread and can have deleterious effects. The unintended consequences of prolonged therapy include drug toxicity, the emergence of Clostridium difficile infections, and antimicrobial resistance.2
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Hawn MT, Knowlton LM. Balancing the Risks and Benefits of Surgical Prophylaxis: Timing and Duration Do Matter. JAMA Surg. 2019;154(7):598–599. doi:https://doi.org/10.1001/jamasurg.2019.0570
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: