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Comment & Response
July 17, 2019

Prediction of Lymph Node Metastasis in Early Gastric Cancer by Collagen Signature—Endoscopists’ Viewpoint

Author Affiliations
  • 1Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, China
JAMA Surg. 2019;154(11):1074-1075. doi:10.1001/jamasurg.2019.2292

To the Editor We read with great interest the article by Chen et al1 reporting a prediction model based on collagen architecture and morphology to estimate the risk of lymph node metastasis (LNM) in patients with early gastric cancer (EGC). The newly developed tools were suggested to be useful in decision-making in the choice of surgical or endoscopic submucosal dissection (ESD) treatment in patients with T1 gastric cancer. However, we have some concerns about this study from the perspective of endoscopists.

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