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Comment & Response
July 24, 2019

Safety and Benefit of Using Liver Grafts From Older Donors

Author Affiliations
  • 1Hepatobiliary and Liver Transplant Unit, General and Digestive Surgery Department, University Hospital Virgen del Rocio, Seville, Spain
JAMA Surg. 2019;154(10):978-979. doi:10.1001/jamasurg.2019.2186

To the Editor We read with great interest the results of the cohort study by Haugen et al1 about liver transplant trends from 2003 to 2016 and the outcomes of older donors. We congratulate the authors for the extensive review and important results.

We found relevant that data show an increase in older donor rejection over time and a decrease in its use. The early decrease in using older donors seems justified after the initial poor results associated with those grafts compared with those of younger donors, as seen in the 2003 through 2009 group. However, the improvement of the overall results as time passes and the higher experience with the use of older donors show enough evidence to justify the use of older donors.

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