[Skip to Content]
[Skip to Content Landing]
Views 376
Citations 0
Comment & Response
August 28, 2019

Ideal Total Joint Arthroplasty Antibiotic Prophylaxis Unknown

Author Affiliations
  • 1Department of Orthopaedic Surgery and Rehabilitation, University of Rochester Medical Center, Rochester, New York
  • 2Division of Adult Reconstruction, Orthopaedic Surgery, University of Rochester Medical Center, Rochester, New York
JAMA Surg. 2019;154(12):1168-1169. doi:10.1001/jamasurg.2019.2902

To the Editor We commend the authors of “Association of Duration and Type of Surgical Prophylaxis With Antimicrobial-Associated Adverse Events” on their investigation efforts into an important topic of discussion.1 They retrospectively reviewed the Veterans Affairs Surgical Quality Improvement Project Database to assess postoperative 30-day surgical site infections (SSIs), 7-day incidence of acute kidney injury (AKI), and development of Clostridium difficile infection at 90 days after cardiac, vascular, colorectal, and orthopedic surgery. They concluded that longer duration of prophylactic antibiotics did not lead to decreased rate of SSI but rather increased rates of AKI and C difficile infection.

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    ×