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Invited Commentary
November 6, 2019

Postoperative Infection—A Pervasive Mediator of Patient Mortality

Author Affiliations
  • 1University of Louisville Department of Surgery, Division of General Surgery, Louisville, Kentucky
JAMA Surg. Published online November 6, 2019. doi:https://doi.org/10.1001/jamasurg.2019.4554

Postoperative infection is responsible for approximately one-fourth of all nosocomial infections and may have an incidence as high as 5%.1 The prevention of this morbidity remains a substantial portion of health care expenditures each year.2 Postoperative infection increases mortality after major operations,3 but despite this fact, much of the previous literature focuses only on its association with 30-day morbidity and mortality.

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