Chen and colleagues1 performed a randomized controlled clinical trial to determine the usefulness of an indocyanine green (ICG) tracer for lymph node dissection during radical gastric cancer surgery. This single-institution study was performed in a tertiary referral center, in which more than 800 gastric resections are performed every year.
Two hundred fifty-eight patients with T1 to T4a gastric cancer were randomized to undergo either a conventional gastrectomy (129 patients) or an ICG tracer-guided laparoscopic D2 gastrectomy (129 patients). The ICG was injected endoscopically in the peritumoral submucosa the day before the operation. The primary end point of the study was the number of retrieved lymph nodes; the secondary end points were the noncompliance rate (defined as the absence of lymph nodes from more than 1 standard lymph node station), morbidity, and mortality.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Patti MG, Herbella FA. Indocyanine Green Tracer-Guided Lymph Node Retrieval During Radical Dissection in Gastric Cancer Surgery. JAMA Surg. 2020;155(4):312. doi:10.1001/jamasurg.2019.6034
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: