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Invited Commentary
March 4, 2020

Bariatric Surgery and Diabetes Treatment—Finding the Sweet Spot

Author Affiliations
  • 1Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison
  • 2William S. Middleton Memorial VA, Madison, Wisconsin
JAMA Surg. Published online March 4, 2020. doi:10.1001/jamasurg.2020.0088

Type 2 diabetes (T2DM) is closely associated with obesity. Given that weight loss is associated with T2DM remission,1 there has been intense interest in diabetes outcomes following bariatric surgery. The landmark Surgical Therapy and Medications Potentially Eradicate Diabetes Efficiently (STAMPEDE) trial found that bariatric surgery was a more effective diabetes treatment compared with medical management after 5 years of follow-up.1 While it was not adequately powered to detect differences between Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), other randomized clinical trials have found no differences in diabetes resolution between RYGB and SG.2,3

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