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Original Investigation
May 6, 2020

Association of Surgical Skill Assessment With Clinical Outcomes in Cancer Surgery

Author Affiliations
  • 1Department of Surgery and Cancer, Imperial College London, London, England
  • 2Department of General Surgery, Yeovil District Hospital National Health Service Foundation Trust, Yeovil, England
  • 3St Mark’s Hospital, Northwick Park, Harrow, England
  • 4National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney, Australia
  • 5Department of Surgery, University of Adelaide, Adelaide, Australia
  • 6Canterbury District Health Board, Christchurch, New Zealand
  • 7Faculty of Medical and Biomedical Sciences, University of Queensland, Brisbane, Australia
  • 8Royal Brisbane and Women’s Hospital, Queensland, Australia
  • 9University College London, London, England
JAMA Surg. Published online May 6, 2020. doi:10.1001/jamasurg.2020.1004
Key Points

Question  Is surgical skill associated with outcome differences following cancer operations?

Findings  In this cohort study, the intraoperative performance of credentialed surgeons within 2 multicenter laparoscopic rectal cancer randomized trials was analyzed using a bespoke objective assessment tool shown to be reliable and valid for the specialist level. Substantial variation in measured skill was present with large differences between upper and lower quartile surgeons (mesorectal fascial plane, 93% vs 59%; 30-day morbidity, 23% vs 50%).

Meaning  Surgical skill is highly associated with histopathological and clinical outcomes and requires consideration in trial design and interpretation.

Abstract

Importance  Complex surgical interventions are inherently prone to variation yet they are not objectively measured. The reasons for outcome differences following cancer surgery are unclear.

Objective  To quantify surgical skill within advanced laparoscopic procedures and its association with histopathological and clinical outcomes.

Design, Setting, and Participants  This analysis of data and video from the Australasian Laparoscopic Cancer of Rectum (ALaCaRT) and 2-dimensional/3-dimensional (2D3D) multicenter randomized laparoscopic total mesorectal excision trials, which were conducted at 28 centers in Australia, the United Kingdom, and New Zealand, was performed from 2018 to 2019 and included 176 patients with clinical T1 to T3 rectal adenocarcinoma 15 cm or less from the anal verge. Case videos underwent blinded objective analysis using a bespoke performance assessment tool developed with a 62–international expert Delphi exercise and workshop, interview, and pilot phases.

Interventions  Laparoscopic total mesorectal excision undertaken with curative intent by 34 credentialed surgeons.

Main Outcomes and Measures  Histopathological (plane of mesorectal dissection, ALaCaRT composite end point success [mesorectal fascial plane, circumferential margin, ≥1 mm; distal margin, ≥1 mm]) and 30-day morbidity. End points were analyzed using surgeon quartiles defined by tool scores.

Results  The laparoscopic total mesorectal excision performance tool was produced and shown to be reliable and valid for the specialist level (intraclass correlation coefficient, 0.889; 95% CI, 0.832-0.926; P < .001). A substantial variation in tool scores was recorded (range, 25-48). Scores were associated with the number of intraoperative errors, plane of mesorectal dissection, and short-term patient morbidity, including the number and severity of complications. Upper quartile–scoring surgeons obtained excellent results compared with the lower quartile (mesorectal fascial plane: 93% vs 59%; number needed to treat [NNT], 2.9, P = .002; ALaCaRT end point success, 83% vs 58%; NNT, 4; P = .03; 30-day morbidity, 23% vs 50%; NNT, 3.7; P = .03).

Conclusions and Relevance  Intraoperative surgical skill can be objectively and reliably measured in complex cancer interventions. Substantial variation in technical performance among credentialed surgeons is seen and significantly associated with clinical and pathological outcomes.

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