Prognosis in pancreatic cancer remains dismal, despite an abundance of investigational efforts and improved multimodality treatment. Extending survival is greatly hindered by delayed diagnosis, which limits therapeutic options. The UK National Institute for Health and Care Excellence (NICE) sought to develop a comprehensive evidence-based guideline to optimize practice and reduce variability in the diagnosis and treatment of pancreatic cancer.
The guideline conception was initiated by NICE and developed by a multidisciplinary committee of physicians, researchers, and lay members. The National Guideline Alliance established the committee, provided methodological support, undertook extensive systematic literature searches, appraised the evidence, and conducted meta-analyses and cost-effectiveness studies. Stakeholder input was solicited during a 6-week public consultation period. The committee disclosed conflicts of interests, and members were withdrawn from discussion according to NICE policy. NICE provided funding for the guideline development.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Habib JR, Wolfgang CL. Synopsis of the UK National Institute for Health and Care Excellence Guidelines on the Diagnosis and Management of Pancreatic Cancer. JAMA Surg. Published online September 09, 2020. doi:10.1001/jamasurg.2020.3751
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: