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Comment & Response
September 9, 2020

Questions Regarding Association Between Preoperative Metformin Exposure and Postoperative Outcomes in Adults With Type 2 Diabetes

Author Affiliations
  • 1Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fourth Military Medical University, Xi’an, China
JAMA Surg. Published online September 9, 2020. doi:10.1001/jamasurg.2020.3769

To the Editor We read with great interest the article titled “Association Between Preoperative Metformin Exposure and Postoperative Outcomes in Adults With Type 2 Diabetes.”1 This retrospective study shows an association between metformin prescriptions provided to individuals with type 2 diabetes before a major surgical procedure and reduced risk-adjusted mortality and readmission after the operation.2 In general, it is a well-designed study; however, we would like to address some questions concerning the content of this article.

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