To the Editor We read with great interest the article by Reitz et al1 published in JAMA Surgery. The study concluded that there is an association between metformin prescriptions provided to individuals with type 2 diabetes before a major surgical procedure and reduced risk-adjusted mortality and readmission after the operation. Although it sounds scientific, there are some problems that deserve our attention.
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Liang H, Ding X, Sun T. Questions Regarding Association Between Preoperative Metformin Exposure and Postoperative Outcomes in Adults With Type 2 Diabetes. JAMA Surg. Published online September 09, 2020. doi:10.1001/jamasurg.2020.3772
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