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Comment & Response
September 9, 2020

Questions Regarding Association Between Preoperative Metformin Exposure and Postoperative Outcomes in Adults With Type 2 Diabetes

Author Affiliations
  • 1General ICU, The First Affiliated Hospital of Zhengzhou University, Henan Key Laboratory of Critical Care Medicine, Zhengzhou Key Laboratory of Sepsis, Zhengzhou, China
JAMA Surg. Published online September 9, 2020. doi:10.1001/jamasurg.2020.3772

To the Editor We read with great interest the article by Reitz et al1 published in JAMA Surgery. The study concluded that there is an association between metformin prescriptions provided to individuals with type 2 diabetes before a major surgical procedure and reduced risk-adjusted mortality and readmission after the operation. Although it sounds scientific, there are some problems that deserve our attention.

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