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Comment & Response
October 14, 2020

Whole-Blood Resuscitation of Injured Patients’ Plasma

Author Affiliations
  • 1SAMU des Yvelines, Centre Hospitalier André Mignot, Versailles, France
  • 2TraumaBase PréHospitalière, Hôpitaux Universitaires Henri Mondor, Créteil, France
  • 3SAMU du Val de Marne, Hôpitaux Universitaires Henri Mondor, Assistance Publique–Hôpitaux de Paris, Créteil, France
  • 4SAMU de Paris, Service d’Anesthésie Réanimation, Centre Hospitalier Universitaire Necker Enfants Malades, Assistance Publique Hôpitaux de Paris, AP-HP.Centre, and Université de Paris, Paris, France
JAMA Surg. 2021;156(1):101. doi:10.1001/jamasurg.2020.4109

To the Editor In the May 13, 2020, issue of JAMA Surgery, Leeper et al1 presented the cold-stored low-titer anti-A and anti-B group O whole blood (WB) as an innovative treatment of hemorrhagic shock and coagulopathy after injury. While the authors must be congratulated for the presentation of this resurgence of whole blood in the paradigm of acute trauma resuscitation, both for prehospital and in-hospital settings, we think that this hemostatic strategy has some intrinsic limitations.

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