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Invited Commentary
November 4, 2020

Choosing Wisely in the Workup of Primary Hyperaldosteronism

Author Affiliations
  • 1Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
  • 2Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
  • 3Department of Surgery, University of California, San Francisco, San Francisco
JAMA Surg. Published online November 4, 2020. doi:10.1001/jamasurg.2020.5025

Minimally invasive adrenalectomy is a safe operation that cures primary hyperaldosteronism (PHA) for patients who are properly selected, at a patient outcome and morbidity cost comparable with laparoscopic cholecystectomy.1 Nevertheless, selection errors can lead to ineffective adrenalectomy in patients with bilateral causes of PHA and remove the chance for cure if the side opposite the side with the pathology is removed.

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