The outcomes of transplant for metastatic disease in the early days of liver transplantation were dismal.1 Early recurrence was common and 3-year survival was unusual. These results, coupled with a shortage of cadaveric organs for transplant, led to an abandonment of transplant as a treatment option for colorectal liver metastases. In this issue of JAMA Surgery, Dueland and colleagues2 present data that see this treatment in a new light.
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Fong Y. Who Should Undergo Transplant for Metastatic Colorectal Cancer? A Shift in Treatment Paradigm. JAMA Surg. Published online March 31, 2021. doi:10.1001/jamasurg.2021.0268
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