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Comment & Response
April 14, 2021

Implant Surface Texture and Breast Cancer Recurrence

Author Affiliations
  • 1Department of Breast Surgery, Hospital Nossa Senhora das Graças, Curitiba, Brazil
  • 2Department of Breast Surgery, Hospital Geral de Fortaleza, Fortaleza, Brazil
  • 3Department of Breast Surgery, Memorial Sloan Kettering Cancer Center, New York, New York
JAMA Surg. 2021;156(7):689. doi:10.1001/jamasurg.2021.0688

To the Editor We read with great interest the study “Association of the Implant Surface Texture Used in Reconstruction With Breast Cancer Recurrence.”1 This is a retrospective cohort study from a single institution in South Korea. The authors compared local and regional recurrence-free survival and disease-free survival rates among patients with smooth and textured implant after reconstruction, finding worse disease-free survival in the textured implant group. It was hypothesized that a chronic inflammatory process could explain the results, just as it happens in breast implant–associated anaplastic large cell lymphoma.2,3 This observation is novel and provocative, but we have some questions on the methodology and possible biases.

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