To the Editor We read with interest the recent JAMA Network Insight by Schwulst and Son on the management of gallstone disease during pregnancy advocating cholecystectomy in all trimesters.1 While the authors emphasized the importance of trimester in the setting of gallbladder disease, their recommendations are based on small case series, as are the SAGES (Society of American Gastrointestinal Endoscopic Surgeons) guidelines. These reports are too small to distinguish the effect of timing of treatment in pregnancy on outcome. Conversely, we recently published a large series of pregnant women with gallstone disease treated in the outpatient, emergency department, and inpatient settings and express concern that recommendations with regard to the third trimester are inappropriate.2
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Fong ZV, Chang DC, Strasberg SM. Nonoperative Management for Pregnant Individuals With Gallstone Disease in the Third Trimester. JAMA Surg. 2021;156(8):795–796. doi:10.1001/jamasurg.2021.0637
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.