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Invited Commentary
April 28, 2021

Gender-Affirming Surgeries and Improved Psychosocial Health Outcomes

Author Affiliations
  • 1Division of Plastic and Reconstructive Surgery, Department of Surgery, Weill Cornell Medicine, New York, New York
  • 2Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 3Johns Hopkins Center for Transgender Health, Johns Hopkins University School of Medicine, Baltimore, Maryland
JAMA Surg. Published online April 28, 2021. doi:10.1001/jamasurg.2021.0953

There is a growing body of literature supporting the positive outcomes of gender-affirming surgery (GAS) on transgender and gender diverse individuals. Mental health outcomes are among the most vital end points to study, given the fundamental intent of GAS to provide patients with relief from gender dysphoria and improvement of psychosocial distress. Much of the data on this topic come from observational studies that lack either control groups or adequate sample size.1,2 In this issue of JAMA Surgery, Almazan and Keuroghlian3 contribute an analysis of the US Transgender Survey (USTS), examining the topic of mental health outcomes following GAS.

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