In Reply We thank Chen et al and Sterpetti for their thoughtful comments on our study1 and appreciate the opportunity to clarify our work. Chen et al expressed concerns regarding the broad-spectrum nature of ciprofloxacin and levofloxacin; this is an excellent point. While we did include augmentin as another broad-spectrum comparator, it is important to note that our study was limited to outpatient oral antibiotic prescription fills. We excluded individuals who were hospitalized within 30 days of their prescription fill, thereby minimizing the probability of including those with severe clinical illness in the analysis.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Newton ER, Strassle PD, Kibbe MR. Concerns About Study on Fluoroquinolone Use and Risk of Development Of Aortic Aneurysm–Reply. JAMA Surg. 2021;156(11):1069–1070. doi:10.1001/jamasurg.2021.3029
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.