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Comment & Response
July 7, 2021

Concerns About Study on Fluoroquinolone Use and Risk of Development Of Aortic Aneurysm

Author Affiliations
  • 1Department of Surgery, Sapienza University of Rome, Italy, Rome, Italy
JAMA Surg. 2021;156(11):1068-1069. doi:10.1001/jamasurg.2021.3026

To the Editor I read with much interest the article by Newton et al,1 which appeared in JAMA Surgery. In a large retrospective study of more than 27 million patients who received fluoroquinolones or counterpart antibiotics, they found an increased prevalence of surgery for abdominal aortic aneurysm within 90 days from antibiotics prescription (7.5 cases per 10 000 fills [6752 of 9 053 961] after fluoroquinolones compared with 4.6 cases per 10 000 fills [17 627 of 38 542 584] after comparator antibiotics).

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