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Invited Commentary
September 1, 2021

Quality of Life and Breast Cancer Surgery

Author Affiliations
  • 1Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York
JAMA Surg. Published online September 1, 2021. doi:10.1001/jamasurg.2021.3759

A central tenet in the use of local therapy for breast cancer is patient choice. Survival and rates of local recurrence do not differ significantly among patients undergoing breast-conserving therapy (BCT) or mastectomy,1 and the widespread use of adjuvant systemic therapy has led to substantial decreases in the risk of local recurrence and contralateral breast cancer,2 making BCT a more attractive choice for patients. Paradoxically, increasing numbers of women with unilateral cancer choose to undergo bilateral mastectomy, and this trend is most pronounced among young women.3 This occurrence presents a challenge for breast surgeons who seek to respect patient autonomy.

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