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Comment & Response
October 13, 2021

No Strong Evidence on Liver Transplant for Colorectal Cancer Liver Metastasis Over Portal Vein Embolization Associated With Liver Resection

Author Affiliations
  • 1Hepatopancreatobiliary Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China
JAMA Surg. 2022;157(2):172-173. doi:10.1001/jamasurg.2021.5124

To the Editor Liver transplant (LT) has already become one of the major approaches to manage advanced liver diseases, including colorectal cancer liver metastasis (CRLM). Dueland et al1 reported their single-institutional retrospective cohort analysis on LT for CRLM, which was compared with those who received portal vein embolization (PVE) with intent to undergo liver resection (LR). Their results were seemingly encouraging but also misleading; as such, shifting treatment paradigm or making LT a new tool for patients with CRLM still remains a question to be weighed further.2,3

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