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Comment & Response
February 16, 2022

Comments on the CAIRO4 Trial Secondary Outcomes Report

Author Affiliations
  • 1Calderdale and Huddersfield NHS Foundation Trust, Huddersfield, United Kingdom
  • 2Department of Oncology and Metabolism, University of Sheffield, Sheffield, United Kingdom
JAMA Surg. 2022;157(6):551. doi:10.1001/jamasurg.2021.7584

To the Editor We write regarding the article by van der Kruijssen et al,1 which we discussed at CRAMSURG, a UK-based online journal club. We would like to congratulate the authors on years of work underlying the conduct and subsequent publishing of this multicenter, multinational randomized clinical trial addressing an important research question. We write to raise a number of issues discussed in our meeting.

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