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Correspondence and Brief Communications
May 2001

Elucidation of Active Anticancer Agents in Naturally Occurring Substances

Arch Surg. 2001;136(5):600. doi:10.1001/archsurg.136.5.600

In their concise study using an allogeneic model, Hamzaoglu et al1 provide evidence that Ehrlich ascites tumor implantation is inhibited by the prior and concurrent local injection of honey. The authors propose that this method of tumor implant prevention may be applicable to the prevention of tumor in surgical wounds, particularly those wounds created during laparoscopic procedures. Tumor implantation in such wounds has complicated the management of colorectal cancer and gallbladder carcinoma.