Two cases of small-bowel perforation secondary to Clostridium difficile enteritis are described and compared with the 8 cases of C difficile enteritis reported in the medical literature. The cause of small-bowel involvement with C difficile is unknown, but prior antibiotic use, prior colectomy, chronic alterations in small-bowel flora, and other host factors are discussed.
Hayetian FD, Read TE, Brozovich M, Garvin RP, Caushaj PF. Ileal Perforation Secondary to Clostridium difficile Enteritis: Report of 2 Cases. Arch Surg. 2006;141(1):97–99. doi:10.1001/archsurg.141.1.97
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