Surgeons smile when a cardiologist during a preoperative consultation suggests that we “avoid intraoperative hypoxia and hypotension.” We know these general aspects of care are important, but little attention has been devoted to quantifying how important they are and linking that information to the related clinical consequences. Regenbogen et al have used multivariable logistic regression analysis to identify 3 factors independently associated with poor outcomes. Now cardiologists might suggest a more informed strategy—“avoid hypotension, blood loss, and bradycardia.”