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Invited Critique
June 15, 2009

Surgical Glove Perforation and the Risk of Surgical Site Infection—Invited Critique

Arch Surg. 2009;144(6):558. doi:10.1001/archsurg.2009.71

This 2-year study by Misteli and colleagues relates SSI to the incidence of surgical glove perforation in more than 4100 general surgery patients. Glove perforation occurred in 16.3% of cases and rose dramatically in cases lasting longer than 2 hours (34.0% vs 9.4%). Surgical site infection was identified in 7.5% of the cases in which there was a glove perforation vs 3.9% when there was none. The essence of the study resides in the multivariate logistic regression analysis, by which glove perforation was found to be a significant risk factor for SSI but only in cases in which prophylactic antibiotics were not used.