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Invited Critique
March 2010

Further Refinement of the Optimal Treatment Following Radical Gastric Resection for Gastric AdenocarcinomaComment on “Adjuvant Chemoradiotherapy in Patients With Stage III or IV Radically Resected Gastric Cancer”

Author Affiliations

Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2010

Arch Surg. 2010;145(3):239. doi:10.1001/archsurg.2010.3

Resection remains the cornerstone of curative treatment for gastric cancer, but it is associated with a cure rate of 25% to 35%. Recent positive results from large phase 3 trials1-3 leave the surgical oncologist with several options. Two accepted standards of care in the West focus on adjuvant CT-RT based on the North American Intergroup 0116 trial and perioperative CT based on the MAGIC trial from Britain.