Open Mesh Repair of Ventral Incisional Hernias With Tacker With Less Complication—Reply

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We appreciate Dr Mohammadhosseini's comments regarding our study.¹ Our primary end point was complications and not recurrence. For recurrence to be the end point, the study will require enrolling 586 patients (assuming a 10% drop-out rate) to detect an 8% difference between the 2 groups, with a power of 80%, α = .05, a follow-up of at least 3 years, and a budget calculated at more than $5 million.