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Article
March 1924

PAGET'S DISEASE OF THE FEMALE NIPPLE: A PREVENTABLE DISEASE, CURABLE IN ITS EARLY STAGES: A STUDY OF THIRTY CASES

Arch Surg. 1924;8(2):461-505. doi:10.1001/archsurg.1924.01120050002001
Abstract

The evidence for the conclusion that Paget's disease of the nipple may be a preventable disease is based on the observation of seven cases in which the lesion of the nipple healed under simple and protective treatment; in two cases there was a red, finely granular nipple, as illustrated in Figure 9, and there were five cases of warts, as illustrated in Figure 5. A sixth case, of a wart of long duration which disappeared under treatment, is described in Case 18.

The conclusion that Paget's disease is largely curable is based on the results in twenty cases in which operation was performed. In seven of these, the microscopic section showed no evidence of malignancy; two cases were examples of the red, finely granular nipple as shown in Figures 1, 2 and 9; three cases presented benign warts, as illustrated in Figure 5, and two cases, superficial ulcers on an

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