Multiple primary cancers arising in one organ are not very common; multiple primary cancers occuring in several organs are comparatively rare; and a combination of both these forms is sufficiently unusual to merit recording in the literature.
Of 1,664 cases of mammary cancer tabulated by Gross,1 only two were bilateral in origin, Billroth2 met with three instances of this kind in 245 mammary cases. According to Nichols,3 of 685 necropsies for cancer in Montreal hospitals, eighteen revealed initial multiplicity.
Kaufman4 mentions a contribution of Kocher's on the simultaneous primary occurrence of ovarian, breast and axillary cancer. Simultaneous primary cancerous disease of the tongue and the jejunum was observed by Abesser;5 of the larynx and the thyroid by Tixier;6 and of the stomach and the uterus by Reutter.7 Simultaneous, primary sarcoma of the gall-bladder and the uterus is described by Schmincke.8
HERLY L. MULTIPLE PRIMARY CANCERS: WITH REPORT OF A CASE. Arch Surg. 1924;9(1):204–214. doi:10.1001/archsurg.1924.01120070207009
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