Several years ago, I devoted considerable time to the study of serial sections of the extremities of human fetuses of different ages, for the purpose of following the development of the periosteum and the different stages in the differentiation of the skeleton. As time goes by, the question as to whether or not the periosteum possesses an osteogenetic function seems no nearer solution than it did centuries ago. This is in all probability due to the fact that observers obtain the wrong point of view from the study of adult tissues.
Recently, Haas has given a résumé1 of the work that has been done to prove or disprove that the periosteum has an osteogenetic function. From a survey of the facts already put forth in the literature, it becomes very evident that the embryonic history of the periosteum has been quite neglected in the current discussions, although fully considered
BLAISDELL FE. THE OSTEOGENETIC FUNCTION OF THE PERIOSTEUM. Arch Surg. 1925;11(6):933–945. doi:10.1001/archsurg.1925.01120180126007
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