With the demonstration of the etiologic rôle of bacteria in disease, the search for specific remedies could be more intelligently directed; nevertheless, it is a source of both surprise and discouragement to realize how few of these have been placed at our disposal since Pasteur's momentous discoveries. Particular significance is attached to the suggestion of Piper1 that in mercurochrome-220 soluble, intravenously administered, we may possess a specific against various blood stream infections. Young,2 under whose direction this drug was first introduced into therapeutics, immediately acted on Piper's suggestion, and the successes obtained by this author and his co-workers appeared so brilliant that they were, indeed, "tempted to soar into the realms of fancy" and conclude that in mercurochrome-220 soluble they saw the realization of the age old dream of "therapia magna sterilisans," through which could be healed all the ills of the flesh. Unfortunately, however, not all clinical
WILLIS AM, HASKELL CC. THE TREATMENT OF EXPERIMENTAL PERITONITIS BY MERCUROCHROME-220 SOLUBLE: ALONE OR IN CONJUNCTION WITH HYPERTONIC DEXTROSE SOLUTIONS. Arch Surg. 1926;12(5):1080–1085. doi:10.1001/archsurg.1926.01130050134007
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