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Article
July 1926

PARTIAL TRACHEAL OBSTRUCTION: AN EXPERIMENTAL STUDY IN THE EFFECTS ON THE CIRCULATION AND RESPIRATION OF MORPHINIZED DOGS

Author Affiliations

NASHVILLE, TENN.; BOSTON
From the departments of surgery, medicine and pathology of the Johns Hopkins University Medical Department.

Arch Surg. 1926;13(1):81-95. doi:10.1001/archsurg.1926.01130070084006
Abstract

In the course of some observations on the blood gases in asthma,1 certain findings indicated significant changes in the circulatory mechanism. Recently there has been an opportunity to make similar studies on two patients with acute laryngeal edema and interesting changes were found in the blood gases and blood reaction. Though the clinical studies have been temporarily abandoned because of a lack of material, the findings in asthma and acute laryngeal edema led to a series of controlled observations on experimental respiratory obstruction in dogs.

The problem was to study the effects of partial tracheal obstruction on the blood gases, blood reaction and volume flow. The object of the present article is to report the results of these experiments.

METHOD  Since asthma is difficult to produce in dogs and the experimental production of laryngeal edema is unsatisfactory, the following technic was employed to produce tracheal obstruction:Dogs of from

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