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August 1926


Arch Surg. 1926;13(2):228-261. doi:10.1001/archsurg.1926.01130080077003

This discussion will deal practically exclusively with infection produced by bacteria of the aerobic variety. I have little experience with the infections produced by anaerobic organisms except as these take part and are found in cases of intrapulmonary suppuration. The little I can say is that, clinically, established infection by anaerobic bacteria is usually produced by mixed infection with more than one organism; that the latter are probably originally secondary invaders and when centered in the foci of pulmonary suppuration are productive of slight or moderate grades of damage, and that when inoculated into a previously uninfected tissue, as happens after operations of the lobectomy type, the resulting pathologic change is extensive and of maximum intensity and results in death in 50 per cent, or more of the cases.

TERMINOLOGY  In medical literature the phenomena of bacterial infection are associated with the usage of the following terms: sepsis, sapremia, septicemia,