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Retention of nitrogen bodies in the blood stream is the most important characteristic of a form of general intoxication of the body which is a common factor in a number of clinical conditions associated with disease of the liver, with disease of the intestinal tract and with disease of the urinary tract. Obstruction to the natural outflow of the normal excretions in each of these three sets of organs is frequently found, clinically, with this form of general intoxication. Evidently there is a common cause for the development of this intoxication, or a group of causes which, because of a common mechanism in the normal interrelated functions of these generally allied groups of organs, results in a common secondary lesion to which the retention of nitrogen bodies in the blood is due.
A cursory view of the facts available in this general class of disease brings the conviction that this
WILENSKY AO. RELATION OF NITROGEN BODIES OF BLOOD TO SURGICAL PROBLEMS IN LIVER AND IN BILIARY TRACT DISEASE: I. INTERRELATIONSHIPS OF NITROGEN BODY METABOLISM AND CRITERIA ON WHICH JUDGMENTS ARE TO BE BASED. Arch Surg. 1927;14(5):955–967. doi:10.1001/archsurg.1927.01130170003001
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