One of the frequently discussed problems of the present day is the use of gentian violet and mercurochrome in the treatment of disease and infection. The type of infection treated has not been limited to one group of cases. The exact nature of the reaction of these drugs in combating infection has not been satisfactorily explained. With this thought in mind, a study has been made of the reaction of gentian violet in joints infected with Staphylococcus aureus. This study has involved a careful investigation of this type of arthritis, and it is hoped that some light may be thrown on arthritis in general.
Churchman has published three articles on the treatment of infections of the joint with gentian violet. First, in 1915, he1 demonstrated an apparatus for the irrigation of a joint, followed by an instillation of gentian violet. He felt that in joints with a purulent infection
SHANDS AR. PYOGENIC ARTHRITIS IN THE KNEE JOINT OF RABBITS: TREATMENT WITH GENTIAN VIOLET: EXPERIMENTAL STUDY. Arch Surg. 1928;16(5):1039–1074. doi:10.1001/archsurg.1928.01140050063005
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