—Wile and Butler32 analyzed the records and physical observations in eighty-eight patients affected with Charcot's arthropathy, and came to the following conclusions:The greatest age incidence was between 35 and 55 years. In the majority of cases the onset was gradual and insidious and extended over a period of months or years. The occasional sudden production of the condition was frequently the result of trauma bringing into visibility a preexisting subclinical process. The condition occurred three times more frequently in men than in women as compared with the incidence of tabes. Polyarticular involvement was common, no joint in the body being immune, but involvement of the knees and ankles occurred far more commonly than did any other form. Cerebrospinal syphilis was present in the majority of cases. Its absence, however, in typical cases indicated that it was not the essential primary etiologic factor. When present, the
WILSON PD, BROWN LT, SMITH-PETERSEN MN, et al. FORTY-SECOND REPORT OF PROGRESS IN ORTHOPEDIC SURGERY. Arch Surg. 1930;21(4):702–716. doi:10.1001/archsurg.1930.01150160149008
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