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Article
December 1930

ALVEOLAR GAS EXCHANGES AND ATELECTASIS: THE MECHANISM OF GAS ABSORPTION IN BRONCHIAL OBSTRUCTION

Author Affiliations

Professor of Clinical Surgery and Research Associate in Surgery; Research Assistant in Surgery NEW YORK
From the Department of Surgical Research, Cornell University Medica College. This work was aided by a grant from the National Research Council and a gift of Mrs. John L. Given in support of surgical research.

Arch Surg. 1930;21(6):1214-1281. doi:10.1001/archsurg.1930.01150180330021
Abstract

Physiology

Requirements of Gas Exchanges

Solubility, Diffusion and Osmosis

Solubility Coefficient

Diffusion Pressure

Osmotic Pressure

The Dissociation Curve of Hemoglobin in Relation to Respiration

The Regulation of Respiration and Circulation

Composition of the Alveolar Air

Venous Blood

Experimental

Technic

Intrabronchial Cannulas

Closed Chest Experiment

Open Chest Experiment

Material and Purpose of Investigation

Problems Investigated

Fate of Alveolar Air Entrapped in a Pulmonary Lobe After Complete Occlusion of Corresponding Bronchus

Changes Produced in Entrapped Alveolar Air as Indicated by Successive Gas Analysis

Is Entrapped Air Absorbed and at What Rate?

Speed of Absorption of Gases of Alveolar Air Introduced Individually in Atelectatic Lung of Living Animal and Gas Exchange That Takes Place Thereafter

Results Following Introduction of Neutral Gases Separately Into Atelec tatic Lung

Behavior of Respiratory Membrane Toward Anesthetic Gases or Vapors

Changes, if Any, in Intrapulmonary Pressure in Occluded Lung During Process of Absorption

Absorption of Various Gases by

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