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Article
October 1932

THE BREAKING STRENGTH OF HEALING FRACTURED FIBULAE OF RATS: IV. OBSERVATIONS ON A HIGH CARBOHYDRATE DIET

Arch Surg. 1932;25(4):722-748. doi:10.1001/archsurg.1932.01160220110004
Abstract

In previous papers we have considered the effect of a standard diet1 and of a high fat diet2 on the breaking strength of healing fractured fibulae in albino rats. In our present paper we shall report the results of a study of the influence exerted on the breaking strength of similar fractures by a high carbohydrate diet.

The absorption of calcium and phosphorus from the gastro-intestinal tract has been shown to be favored by acidic intestinal contents.3 Consequently the foods that produce such contents are advantageous in the assimilation of these salts. Lactose, for one, establishes acid-producing flora in the intestine, while corn starch changes the reaction of the tract but slightly.4 In agreement with the changes in the hydrogen ion concentration produced by these two carbohydrates, it has been demonstrated experimentally that lactose increases the absorption of calcium and phosphorus, while starch diets are followed

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