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In order to determine the worth as well as the limitations and dangers of the various new anesthetic agents, it is desirable that reports of many cases from different clinics be made. With this in view I have undertaken a critical analysis of the cases in which avertin was used either as the anesthetic or for basal narcosis supplemented with some form of inhalation anesthesia in the surgical clinic of the University of Michigan Hospital. This statistical survey covers the period from November, 1929 (when avertin was first adopted in this clinic), to January, 1932, and comprises 430 cases. Operations done in the divisions of genito-urinary and orthopedic surgery in which avertin was employed are included, but the cases in the neurosurgical field have been reserved for a separate report. While avertin was not used as a routine measure for any particular type of work, it was employed rather extensively