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February 1933


Author Affiliations

Associate Surgeon, the Mary Imogene Bassett Hospital COOPERSTOWN, N. Y.; Instructor in Medicine, Hospital of the University of Pennsylvania PHILADELPHIA
From the Laboratory for Surgical Research of the Harvard Medical School, Boston.

Arch Surg. 1933;26(2):323-329. doi:10.1001/archsurg.1933.01170020157013

Two experimental procedures are included in this report: (1) the production of pulmonic stenosis in dogs and (2) the conversion of this lesion into stenosis with insufficiency by partial valvulectomy.

THE PRODUCTION OF PULMONIC STENOSIS  The method was similar to that devised for creating a chronic, sclerosing lesion of the mitral valve, which was reported in a previous paper.1 Two distinct procedures were carried out: (a) electrocoagulation of the pulmonic valve and (b) intravenous inoculation with cultures of Streptococcus viridans.

(a) Electrocoagulation of the Pulmonic Valve.  —One-half hour after the administration of morphine hypodermically, the dog was anesthetized with ether, and both sides of the thorax were shaved and cleansed with soap and water. When the animal was fully relaxed, a properly fitting rubber tube was introduced into the larynx through the trachea and attached to a Wolff bottle containing ether, which was, in turn, attached to an Erlanger

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