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Article
December 1933

ACTION OF CATHARTICS ON ISOLATED DOG'S COLONII. MOTOR ACTIVITY

Arch Surg. 1933;27(6):1130-1145. doi:10.1001/archsurg.1933.01170120154008
Abstract

In a previous report1 experiments relating to the secretory activity of an isolated segment of the dog's colon were considered. This study concerns the motor activity of the isolated colon under the influence of a similar series of drugs.

The movements of the proximal portion of the colon in most animals are both peristaltic and antiperistaltic, and although in man those of the latter type have not been definitely identified, there seems to be no doubt of their presence. Other movements take place here, such as segmentation, serial sectioning, haustral changes, propulsive peristalsis and possibly mass movements, so that the total effect is a thorough mixing, kneading and churning of the content, resulting in conditions facilitating absorption.

METHOD OF INVESTIGATION  In this study dogs were used, and although it is true, as many observers have stated, that the colon of the dog is distinctly of the type found in

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